We are committed to provide free educational services to needy students, As per the policy of Biolearning academy at least 1000 MCQ type question are to provided in public domain, these questions are from the test series of academy, we are in the process of building our database, we hope you will understand that the process is time consuming.
Keep visiting for updates.....
Keep visiting for updates.....
Topic: Plasma membrane & transport across membrane
1.
Which of the following lipids is commonly found in biological membranes?
a. monoglycerides b. diglycerides c. triglycerides d. none of the above
2.
The primary thermodynamic factor favours the formation of a lipid
bilayer in aqueous surroundings is
a. hydrogen
bonds b. hydrophobic effect
c. ionic
interactions d. covalent bonds
3.
Lipids that are found in biological membranes
a. are amphipathic
b. are commonly referred to as triacylglycerols
c. lateral diffusion of lipids
d. lateral diffusion of integral and peripheral proteins
4.
Generally accepted features of biological membrane include all of the
following except
a. asymmetric arrangement of lipids
b. rapid diffusion of inorganic ions across lipid bilayer
c. lateral diffusion of lipids
d. lateral diffusion of integral and peripheral proteins
5.
When an ion or solute is moved against a concentration gradient using
energy, the process Is called
a. diffusion b.
transport
c. active transport d.
regulated diffusion
6.
In the fluid-mosaic model of the membrane
a. the protein is arranged in layers
b. the lipid has no specific arrangement
c. the lipid is fluid and arranged in a bilayer with functional protein
embedded in them.
d. lipids and proteins are not arranged in any particular oder
7.
The correct decreasing order of permeability through a lipid bilayer of
the molecules/ions isoleucine, Tyrosine, O2 and Na+ is
a. O2 > Na+ > Isoleucine, > Tyrosine b. O2 > Isoleucine > Tyrosine > Na+
c. Isoleucine > Tyrosine > O2 > Na+ d. Isoleucine > Tyrosine > Na+ > O2
8.
Which of the following statements about biological membranes is not
true?
a. they contain carbohydrates that are covalently bound to proteins and
lipids
b. they are large sheet-like structures with closed boundaries
c. they are symmetric because of the symmetric nature of lipid bilayers
d. they contain specific proteins that mediate their distinctive
functions
9.
The order of the predicated rate of diffusion across a lipid bilayer
(highest to lowest) is
a. toluene, galactose, phenylalanine, chloride ion
b. chloride ion, phenylalanine, galactose, toluene
c. galactose, phynylalanine, chloride ion, toluene
d. toluene, phynylalanine, galactose, chloride ion
10.
Which one of the following is not a membrane lipid?
a. cholesterol b.
phosphoglyceride
c. cerebroside d.
Choline
11.
All membrane processes, such as pumping and channeling of molecules are
carried out by
a. lipid b. carbohydrate
c. nucleic acid d. proteins
12.
Membrane potentials inside and outside of the membrane are caused by the
unequal distribution of
a. ions b.
fatty acids
c. glucose d. IP3
13.
In Robertson’s unit membrane model of plasma Membrane
a. proteins on cytoplasmic and non-cytoplasmic sides are same
b. proteins on cytoplasmic and non-cytoplasmic sides are different
c. proteins are globular
d. none
14.
Carbohydrates presents on the plasma membrane
a. haves structural role b. forms channel
c. acts as carrier d. helps in molecular
recognization
15.
Carbohydrates occurring, in the cell membrane are
a. glycogen and other polysaccharides b.
oligosaccharides
c. mucopolysaccharides d. monosaccharides
16.
The following statement about biological membrane is correct
a. they are symmetric bi-leaflet structure
b. their constituent lipid and protein moieties are held together by
covalent interaction
c. they are rigid assemblies of protein, lipid and carbohydrates
d. their lipid moieties are amphipathic in nature
17.
Osmosis is a form of diffusion in which
- the solute moves freely
from a region of higher concentration to lower concentration through semipermeable membrane
- the solvent move through
a semi permeable membrane from region, where a solute is in higher concentration to region of lower
concentration
- the solvent moves through
a semi permeable membrane from region where is a solute is in lower concentration to a region of
higher concentration
- none
18.
Which of the following is a function of plasma Membrane?
a. structural barrier and cell communication
b. metabolic activities and cell adhesion
c. mass flow regulation, active transport, diffusion, endocytosis and
exocytosis
d. all
19.
Select the false statement
a. facilitated diffusion is faster than simple diffusion
b. facilitated diffusion exhibits saturation kinetics
c. facilitated diffusion is not very selective
d. facilitated diffusion can be inhibited by agents known to denature
proteins
20.
‘Permease’ a carrier protein, present in the plasma membrane is involved
in the
a. passive transport of molecules
b. active transport of molecules
c. both active and passive transport of molecules
d. none
21.
In simple diffusion process, molecules (solutes) cross the plasma
membrane
a. against concentration gradient b. along concentration gradient
c. do not depends on concentration d. with the help of energy
22.
Transport of molecules through channel protein present in the plasma
membrane is
a. always passive b. always active
c. may be passive or active d. none
23.
Normally the process of osmosis, the net flow of water molecules into or out of the cell depends upon differences in the
a. concentration of water molecule inside and outside the cell
b. rate of molecular motion on either side of the cell membrane
c. concentration of solute molecule inside and outside the cell
d. none
24.
Na+ - K+ ATPase pump use one ATP to pump out
a. 3 Na+ from cell b. 2 Na+ from cell
c. 4 Na+ from cell d. 8 Na+ from cell
25.
Free fatty acids enter cell by
a. passive diffusion b. active diffusion
c. cannot enters into the cell d.
none
26.
Which of the following is not related to facilitated Diffusion?
a. solutes are moved by a change in shape in the carrier protein
b. the process is passive
c. the process require energy input
d. both a and c
27.
Movement of substances across cell membrane is controlled by the
a. size of permeating particles b.
permeability of membrane
c. membrane protein d
.all
28.
Which of the following events require energy?
a. pinocytosis b. Na+
- K+ pump
c. phagocytosis d. all
29.
A poikilothermic organism living in the Arctic would have, compared to
that organism living in the temperate climate zone, a plasma membrane richer in
a. cholesterol b.
long chain fatty acids
c. protein d.
unsaturated fatty acids
30.
Diffusion across the plasma membrane is more rapid if a substance is
a. protein b.
hydrophilic
c. high in its oil : water partition coefficient d. large and globular in shape
31.
A difference between simple diffusion and facilitated transport is that
facilitated transport
a. is concentration dependent
b. occurs across plasma membrane
c. required membrane proteins
d. utilizes a substance moving with its concentration gradient
32.
In plasma membrane, carbohydrate present on the
a. both layer of lipid b. only on cytoplasmic side of
lipid layer
c. only on non-cytoplasmic side of lipid layer d.
None
33.
Most abundant lipid in plasma membrane is
a. cholesterol b. sterol
c. glycolipid d. Phospholipids
34.
In biological membrane, integral proteins and lipids interact mainly by
a. covalent bond b. H-bond
c. Hydrophobic interactions d. Vander Waal force
35.
Liposome is
a. closed, solvent filled vesicles have a single bilayer of fatty acid
chain
b. closed, solvent filled vesicles have a single layer of fatty acid
chain
c. a structure made up of protein
d. both a and c
36.
Major force responsible for the formation of lipid bilayer
a. Vander Waal force b.
Covalent bond
c. Electrostatic interaction d. Hydrophobic force
37.
An artificial membrane composed only of
phospholipids has significant permeability to
a. water b. Na+
c. sucrose d.
glucose
38.
Which of the following will affect active transport?
a. absence of O2 b.
cyanide
c. denaturing agents d. all
39.
Proteins that are embedded in are characterized by
a. a stretch of at least 16 to 21 hydrophobic amino acid in their
primary structure
b. a high lysine, arginine and histidine content
c. a high glutamate and aspartate content
d. at least one α–helical or β-sheet domain
40.
Which statement is false?
a. phospholipids, glycolipids, and sphingomyelin are all polar lipids
found in natural membrane
b. steroids are found in membranes of animal cells but not in the
membranes of plants cells
c. many membrane components are amphipathic
d. integral proteins in natural membranes may span the whole membrane or
may be anchored to the membrane by lipid
anchors
41.
Which one of the following receptors is associated with an ion channel
a. acetylcholine receptors b. EGF receptor
c. Corticosteroid receptor d. Growth hormone receptor
42.
With respect to the plasma membrane, most enzymatic receptors are
a. single pass b.
seven pass
c. entirely on the surface d. multipass
43.
A membrane transport protein is said to be a “carrier” protein if
a. it forms an open pore through which a molecule can diffuse
b. an electrochemical gradient is necessary for transport to occur
c. it only allows transport “down” a concentration gradient
d. it binds to the molecule and changes shape during transport.
44.
A “passive” membrane transport protein
a. will require a direct source of energy for the transport to occur.
b. can only transport a molecule ‘down’ a gradient
c. involves a ‘carrier’ type transport mechanism only
d. can move a molecule ‘up’ a gradient if a membrane potential exists
45.
Suppose you were to treat a normal mammalian cell with a substance that
inhibits the Na-K ATPase. What would be the most immediate effect upon the
cell?
a. there would be no change at all
b. the cell’s osmotic balance were be disrupted, and the cell would
begin to swell
c. the cell membrane potential would immediately drop to zero
d. the cell would very quickly run out of ATP
46.
Transport across a membrane is said to be ‘coupled’ when
a. two molecules are transported across the
membrane in the same direction
b. membrane transport is coupled to an energy
source, such as ATP hydrolysis
c. transport of one ion down its gradient provides
the energy to transport another molecule against its gradient
d. both the concentration gradient and membrane
potential determine the rate of transport across the membrane
47. ATP-
binding cassette (ABC) transporters:
a. are all P-glycoproteins
b. are found only in eukaryotes
c. are both; a membrane-spanning domain
that recognizes the substrate and an ATP-binding domain
d. affect translocation by forming
channels
48.
Phosphatidyl serine, an important component
of biological membrane, is located in
a. the outer leaflet but flipflops to
inner leaflet under specific conditions.
b. both the leaflets.
c. the middle of the bilayer
d. the inner leaflet but flipflops to
outer leaflet under specific conditions.
49.
Which
of the following statements about transport across biological membranes is TRUE?
a.
As the concentration of the
transported molecule/ion is increased, both carrier proteins and ion channels
saturate
b.
As the concentration of the
transported molecule/ion is increased, carrier protein do not saturate but ion
channels saturate
c. As the concentration of the
transported molecule/ion is increased, carrier proteins saturate but ion
channels do not saturate
d.
As the concentration of the
transported molecule/ion is increased, carrier proteins and ion channels both
proportionately increase the rate of transport and do not show saturation
50.
Ionophores
are:
a. the gating mechanisms
associated with the transport of ions
b. intrinsic proteins that
passively transport ions
c. chemicals that form pores in
the plasma membrane and allow ions to cross
d. intrinsic proteins that
actively transport ions
(Answer Key) All suggestions and corrections (if any) are invited.
1.b 2.b 3.a 4. b 5.c
1.b 2.b 3.a 4. b 5.c
6.c 7.b 8.c 9.d 10.d
11.d 12. a 13.b 14.d 15.b
16.d 17.c 18.d 19.c 20.a
21.b 22.a 23.c 24. a 25.a
26.c 27.d 28.d 29.d 30.c
31.c 32.c 33.d 34.c 35.a
36. d 37.a 38.d 39.? 40.b
41.a 42.d 43.d 44.b 45.c
46.c 47. c 48. d 49. c 50. c
Topic: Linkage, Crossing over, Recombinations, Gene Maps
11.d 12. a 13.b 14.d 15.b
16.d 17.c 18.d 19.c 20.a
21.b 22.a 23.c 24. a 25.a
26.c 27.d 28.d 29.d 30.c
31.c 32.c 33.d 34.c 35.a
36. d 37.a 38.d 39.? 40.b
41.a 42.d 43.d 44.b 45.c
46.c 47. c 48. d 49. c 50. c
Topic: Linkage, Crossing over, Recombinations, Gene Maps
1. Recombination frequencies
A. are the same for all genes.
B. arise from specific genetic exchange
between non-homologus chromosomes
C. are the same for cis and trans
heterozygotes.
D. decrease with distance.
2. The maximum recombination frequency
between two genes is
A. 100% B.
80% C.
50% D. 10%
3. In crossing over
A. Genetic exchange occurs before chromosome
replication
B. The probability of its occurrence
decreases with increasing distance between the genes exchanged
C. Occurs between two loci very close
together
D. The reciprocal exchange between
homologous chromosomes is random
4. In a four-point testcross the number of
phenotypic classes of progeny expected is
A. 4 B.
8 C.
16 D.
32
5. Two genes with a 50% recombination
frequency are
A. Present on homologous chromosomes B.
Located close by
C. Linked D.
Far apart on a single chromosome
6. In Drosophila,
the genes r and s are linked. Flies of
genotype r+ s+/ r+ s+
and r s/ r s are crossed and an F1 obtained.
The F1 allele arrangement is called
A. Cis B.
Trans C.
Recombinant D.
Complementary
7. Which of the following
statements is true regarding recombination between genes on homologous chromosomes:
A. Equivalent ratios (1:1:1:1) are found in
progeny from homozygous dihybrid crosses
B. Recombination frequencies are greater
than 50%
C. 25% of each genotype will appear among
the progeny from dihybrid crosses
D. Exchange of the middle pair of alleles
occurs in double crossovers
8. Maize has 10 pairs of chromosomes,
linkage groups present in it are:
A. 5 B.
10 C.
20 D.
40
9. The evidence that crossing over occurs at
4 strand stage comes from:
A. Study of linkage maps in Drosophila B. Study of
meiosis in maize
C. 4: 4 arrangement of Neurospora ascospores D. 2:2:2:2 arrangement of
Neurospora ascospores
10. Out of 800 progeny of a
three-point testcross there were 24 double crossover recombinants, whereas 30
had been expected on the basis of no interference. The interference is
A. 0.05 B.
0.10 C. 0.20 D.
0.50
11. An organism heterozygous
for three genes AaBbCc was mated to a
homozygote aabbcc, resulting in the
progeny distribution below.
ABC 327
aBC 44
AbC 30
ABc 3
abC 4
aBc 45
Abc 28
abc 319
-----
800
Calculate recombination frequencies between each
gene:
A. A-C =9.8%,
C-B =10.2%, A-B=18.4% B. A-C=18.4% C-B= 9.8% A-B= 10.2%
C. A-C= 9.8%
C-B= 18.4% A-B= 10.2% D. A-C= 18.4% C-B= 10.2% A-B= 9.8%
12. In the above example what is the correct gene order:
A. B-C-A B.
A-C-B C. A-B-C D.
C-B-A
13. In silkmoths
(Bombyx mori), red eyes (re) and white-banded wing (wb) are encoded by two
mutant alleles that are recessive to those that produce wild-type traits (re+
and wb+); these two genes are on the same chromosome. A moth homozygous for red
eyes and white-banded wings is crossed with a moth homozygous for the wild-type
traits. The F1 have normal eyes and normal wings. The F1 are crossed with moths
that have red eyes and white-banded wings in a testcross. The progeny of this
testcross are:
wild-type
eyes, wild-type wings 418
red
eyes, wild-type wings 19
wild-type
eyes, white-banded wings 16
red
eyes, white-banded wings 426
What is the genetic distance between the genes for red
eyes and white-banded wings?
A. 96 map units B.
2 map units C.
4 map units D. 1
map unit
14. Genes ho and dp are 9.0 map
units apart, and genes dp and da are 26.3 map units apart. What is the
probability of a double crossover in these regions?
A. 1.3% B.
2.3% C.
3.4% D.
4.5%
15. The strength of linkage is
A. Inversely proportional to distance between the
genes
B. Directly proportional to the distance between the
genes
C. Directly proportional to the number of cross overs
D. Inversely proportional to the number of chromosomes
(Answer Key)
1. C 2.C 3.
D 4. C 5. D
6. A 7. D 8.
B 9. D 10. C
11. A 12. B 13.
C 14. B 15. A
No comments:
Post a Comment